The Role of Interleukin-23 Inhibition in the Treatment of Psoriatic Arthritis

Psoriatic arthritis is a chronic inflammatory autoimmune disease with varied manifestations, including functional limitation and reduced quality of life. Improved understanding the immunopathogenesis psoriatic arthritis, particularly role interleukin-23 interleukin-17 axis, has led to development therapeutic targets alter natural history condition. In this article, we review monoclonal antibodies targeting p19 subunit in treatment arthritis.